Enzymes and Inhibitors
Zymo Research Corporation 5-hmC Glucosyltransferase, 100 U
Glucosylation of 5-hydroxymethylcytosine by 5hmC Glucosyltransferase can be used for sequence specific (see Cat. Nos. D5410 & D5411), locus specific, as well as global quantification of 5- hydroxymethylcytosine.
Zymo Research Corporation 5-hmC Glucosyltransferase, 200 U
Glucosylation of 5-hydroxymethylcytosine by 5hmC Glucosyltransferase can be used for sequence specific (see Cat. Nos. D5410 & D5411), locus specific, as well as global quantification of 5- hydroxymethylcytosine.
CPC Scientific Glp-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro-OH (trifluoroacetate salt) 25MG
Nonapeptide capable of inhibiting the conversion of angiotensin I to angiotensin II, in vitro and in vivo. Bradykinin Potentiator.SEQUENCE: Glp-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: Glp-WPRPQIPPMOLECULAR FORMULA: C53H76N14O12MOLECULAR WEIGHT: 1101.3STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [35115-60-7]SYNONYMS: RESEARCH AREA: CardiovascularREFERENCES:M.A. Ondetti et al., Biochemistry, 10, 4033 (1971)H.S. Cheung and D.W. Cushman, Biochim. Biophys. Acta, 293, 451 (1973)L.C. Martin et al., Biochem. J., 184, 713 (1979)D.I. Marlborough et al., Arch. Biochem. Biophys., 210, 43 (1981)SKU(s): ACEI-001A, ACEI-001B, ACEI-001C
Ubpbio N-terminally 6xHis-tagged recombinant human UbC13/UEV1A (UbE2N), a ubiquitin conjugating enzyme catalyzing formation of K63 polyubiquitin chains
UbE2N (Ubc13/UEV1A) is a complex that acts as an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Uev1a must interact with Ubc13 because it lacks the active site that other E2s posses. Ube2N has been known to catalyze K63 – linked Ub chains which aides in activation of kinases in NF – kappaB signaling pathway, amongst other tasks.
Sigma Aldrich Fine Chemicals Biosciences Endoproteinase Glu-C from Staphylococcus aureus V8 Type XVII-B, lyophilized powder, 500-1,000 units/mg solid | 66676-43-5 | MFCD01324998 | 2.5KU
Endoproteinase Glu-C from Staphylococcus aureus V8 Type XVII-B, lyophilized powder, 500-1,000 units/mg solid | 66676-43-5 | MFCD01324998 | 2.5KU
Cayman Chemical N-Oleoyl GlutamIn 1mg
An endogenous N-acyl amine; induces mitochondrial uncoupling to increase respiration in C2C12 cells by 64% at 50 µM; inhibits capsaicin-induced calcium flux in HEK293A cells co-transfected with TRPV1 and RFP; reduces the number of acetic acid-induced abdominal constrictions, as well as formalin-induced paw licking in mice at 100 mg/kg
Cayman Chemical Hexnoyl-Coenzyme AsodIum s 1mg
A medium-chain fatty acyl CoA; the preferred acyl donor substrate for GOAT; a precursor in the biosynthesis of olivetolic acid
LGC GENOMICS LLC (Lucigen) Exonuclease III, 25,000 U @ 200 U/LDigest duplex DNA in a 3 to 5 direction from a nick, blunt end, or 3-recessed end, producing stretches of ssDNA.
Produce stretches of ssDNA in dsDNA templates containing nicks, blunt ends or recessed 3' endsProtect protruding 3' ends because this exonuclease will not start digestion at protruding 3' overhangsThis product includes both Exonuclease III enzyme and a 10X reaction buffer.
Medchemexpress LLC Heclin | 890605-54-6 | 98.2% | 283.32 g/mol | C17H17NO3 | 5 MG
Heclin is a small-molecule inhibitor of HECT-family E3 ubiquitin ligases used as a research reagent. It inhibits Smurf2, Nedd4, and WWP1 with micromolar potency and is used in studies of ubiquitin-mediated signaling and cancer biology. Supplied as a powder with recommended cold storage for stability.
- Inhibits Smurf2, Nedd4, and WWP1 (IC50 ≈ 6-7 μM).
- High purity (~98.2%) suitable for biochemical assays.
- Available in small research quantities (5 mg) as a powder.
- Recommended storage: powder -20°C for long term; in solvent -80°C for extended storage.
- Intended for research use only; not for human or veterinary use.
Rockland Immunochemicals BETA GALACTOSIDASE UNCONJUGATED - 0000-17
Beta Galactosidase is used as a control in beta-galactosidase based immunological assays.
Sigma Aldrich Fine Chemicals Biosciences Factor X Activated (Xa) from Bovine Plasma | 9002-05-5 | MFCD00163610 | 50ug
Factor X Activated (Xa) from Bovine Plasma | 9002-05-5 | MFCD00163610 | 50ug
New England Biolabs, Inc. Sce PUS1 – 5000 pmol
Sce Pseudouridine Synthase I (Sce PUS1) is expressed as a 6X His tagged recombinant protein and converts Uridine to Pseudouridine in RNA. Sce PUS1 has a preference for Uridines in single stranded RNA regions over Uridines in double-stranded RNA. Optimal substrate is an unstructured RNA that is 15 nt long or longer. Sequence-specific pseudouridine modification by Sce PUS1 is an alternative to randomly incorporated modified nucleosides by RNA polymerases.
Cayman Chemical CISD1 CytosolIc DomaInhumn
Source: Recombinant human N-terminal His-tagged CISD1 expressed in E. coli • Amino acids: 32-108 • MW: 11.3 kDa
Sigma Aldrich Fine Chemicals Biosciences beta-Glucuronidase from Escherichia coli Type VII-A, lyophilized powder, 5,000,000-20,000,000 units/g protein, pH 6.8 (30 min assay) | 9001-45-0 | MFCD00130629 | 5KU
beta-Glucuronidase from Escherichia coli Type VII-A, lyophilized powder, 5,000,000-20,000,000 units/g protein, pH 6.8 (30 min assay) | 9001-45-0 | MFCD00130629 | 5KU